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Item Impacto do estado nutricional pré-transplante nos desfechos clínicos, sobrevida do enxerto e risco de morte em pacientes transplantados renais(Faculdade Ciências Médicas de Minas Gerais, 2020-04-09) Santos, Marina Ribeiro de Oliveira; Nascimento, Evaldo; Oliveira, Raquel Aparecida Salustriano Fabreti deIntroduction: Chronic kidney disease is currently considered a health problem worldwide and protein-energy malnutrition in these patients is frequent and an important predictor of morbidity and mortality. Kidney transplantation can improve patient's quality of life and survival, but complications after the procedure are still significant and may be associated with the recipient's nutritional status. Little consideration is given to nutrition in the preparation phase and in kidney transplant surgery and, therefore, the prevalence of malnourished patients before and after transplantation and the influence of the nutritional status on results after the procedure are still underestimated. Objectives: To assess the impact of the nutritional status in recipients before kidney transplantation on renal function, clinical outcomes, graft survival and risk of death. Material and Methods: In this retrospective cohort study including 451 transplanted patients between 2008 and 2018, at University Hospital of The Faculty of Medical Sciences, an easy to use nutritional screening tool was developed for patients in preparation for kidney transplantation, based on anthropometric, laboratory and clinical data. For this, a risk score was elaborated with these data. The sum of all components of the score varies from 0 to 12 points. The patients were stratified into three groups, according to the final score: G1 (0 to 2 points) = low risk; G2 (2-4 points) = moderate risk and G3 (> 5 points) = high risk of malnutrition. Results: Stratifying the 451 patients based on the pre-transplant risk score, G1 was composed of 90, G2 of 292 and G3 of 69 patients. G1 patients maintained the lowest creatinine levels at the time of hospital discharge after transplantation, when compared to the other two groups (p = 0.012). Transplant recipients from G3 had a higher proportion of graft losses, with the mean graft survival time in months being 100.56 + 46.49 in G1, 94.64 + 54.34 in G2 and 77.76 +49.01 in G3 (p = 0.044). The Kaplan-Meier survival curve showed better survival for patients in G1, when compared to the other groups (p = 0.046). G3 patients had almost three times greater risk of graft loss (Hazard Ratio [HR] 2.94; 95% CI; 1.084-7.996). Sensitized patients and patients with delayed graft function had almost twice the risk (HR 1,904, 95% CI 1,168-3,105; HR 1,921, 95% CI 1,238-2,980) and patients with cellular rejection or humoral rejection had a 2.18 times greater risk (HR 2,180, 95% CI 1,251-3,798) of graft loss. Conclusion: Kidney transplant patients with a higher risk of malnutrition according to the pre transplant score were associated with worse outcomes and graft survival. The nutritional screening tool is easy to be used in clinical practice to evaluate the patient in preparation for kidney transplant.Item Influência do uso da pressão positiva nas vias aéreas sobre os índices de rigidez arterial de pacientes com apneia obstrutiva do sono grave(Faculdade Ciências Médicas de Minas Gerais, 2020-07-16) Pereira, Patrícia de Souza Pinto; Machado, Maria da Gloria Rodrigues; Silva, José Felippe Pinho daIntroduction: Obstructive sleep apnea (OSA) and arterial stiffness are associated with an increased risk of cardiovascular morbidity and mortality and worsening patients' quality of life. Studies of the association between reduced arterial stiffness and cardiovascular risk with adherence to treatment with positive airway pressure (PAP) by individuals with OSA are not well established. Objetive: To evaluate the impact of PAP therapy on arterial stiffness, quality of life and sleep in patients diagnosed with severe OSA. Method: 43 patients with OSA participated in this study, being 21 users of PAP (OSA-PAP) and 22 non-users (OSA C). Arterial stiffness was assessed by the brachial oscillometry device and quality of life by the specific Quebec Sleep Questionnaire (QSQ). Results: In this case-control study, pulse wave velocity (PWV) was similar in both groups (9.22 ± 1.52 versus 8.44 ± 1.28, p = 0.090), and augmentation index (AIx @ 75) was significantly higher in the OSA-PAP group (28.95 ± 8.53 versus 21.44 ± 9.46, p = 0.035). In the OSA-PAP group, the multiple regression model identified that the variable, total time of use of PAP explained 45.0% of the AIx @ 75 variability [F (1.17) = 13.898; p <0.001; R²: 0.450. The OSA-PAP group had better cardiac function, evidenced by the greater stroke volume (64.41 ± 12.67 versus 72.83 ± 10.5 ml, p = 0.048) and lower heart rate (75 ± 13 versus 65 ± 12 bpm, p = 0.014). The sub-items of the QSQ questionnaire were similar in both groups. Conclusion: The analysis of the positive effects of PAP should not be limited to the impact of this therapy only on quality of life and peripheral blood pressure. The data reveal that AIx @ 75 can be valuable for assessing the stiffness of a patient with severe OSA whose sample is homogeneous and that PAP improves hemodynamic function independently of arterial stiffness. In addition, the total time of use of PAP is negatively related to AIx @ 75.Item Câncer em pacientes transplantados renais: evolução clínica e sobrevida do enxerto e do receptor(Faculdade Ciências Médicas de Minas Gerais, 2020-10-19) Pinto Filho, Valter Alves; Nascimento, Evaldo; Oliveira, Raquel Aparecida Salustriano Fabreti deIntroduction. The end-stage renal disease (ESRD) has become an important public health problem in the world and kidney transplantation is considered the best treatment for ESRD in comparison with dialysis. In order to avoid graft rejection, the transplanted patient underwent continuous treatment with immunosuppressive drugs, whose side effects are associated with the development of different types of cancer (CA) with an important risk factor for mortality. The risk for malignant diseases can increase by two to 20 times in transplant patients. Despite this, cancer screening in the transplant population is inadequate and lacks specific guidelines. Objective. The aim of this study was to analyze the occurrence of cancer in kidney transplant patients, risk factors, clinical evolution and graft and patient survival. Material and methods. This case-control study included 100 patients who received a kidney transplant in the period of 2008 to 2018 at the Transplant Unit of the University Hospital Medical Sciences. Of these, 25 patients who developed CA were assigned to the case group and 75 patients without CA after transplantation were assigned to the control group. All patients were interviewed to survey risk factors such as smoking habit, family history among others before transplant and also screened for malignancies by laboratory and imaging exams. The immunosuppressive therapy was performed with induction immunotherapy in sensitized patients; maintenance triple immunosuppressive therapy using calcineurin inhibitor, methylprednisolone, and sodium mycophenolate. After transplantation, clinical suspicion associated with a positive history of malignancies motivated the initial screening for CA. If CA diagnosis was confirmed, the patient was underwent appropriate treatment. The logistic regression models to obtain the odds ratios and Kaplan-Meier method for survival curves were used in the analyzes. Results. An association of the risk factors as causes of ESRD, time in dialysis, smoking habit, family history of CA, rejection episodes, induction immunotherapy, and maintenance triple immunosuppression with CA development was not observed. Non-melanoma skin cancer was the most common, accounting for 60% of the cases, which was followed by stomach and prostate CA and lymphoproliferative diseases (4% each). The most frequent age range with CA diagnosis was 50–59 years and the highest number of diagnoses was noted from the fifth to seventh year after transplant (43.83%). Graft and patient survival was similar between the groups. Fifty per cent of the patients that died in the case group was due to CA. Conclusion. Association between CA development and the risk factors family history and smoking habit was not observed, and no differences in allograft and patient survival were found between the groups. However, CA can occur early after transplantation, significantly affecting the patient's quality of life. Due to the continuous use of immunosuppression in transplant patients and the high risk of CA, we suggest screening for oncological diseases.Item Simulação de alta fidelidade comparada à de baixa fidelidade no suporte avançado de vida cardiovascular(Faculdade Ciências Médicas de Minas Gerais, 2020-05-08) Alcântara, Rafael Barbosa; Scalabrini Neto, Augusto; Almeida, Alessandra MacielIntroduction: Teaching skills and knowledge using simulation is a useful and important tool for training students in the healthcare students. This teaching model is a constant challenge for institutions and professionals. In a productive and safe environment, there is the possibility of training and assessing students regarding their knowledge, skills and behavioral aspects. In order to achieve that, it uses reliable tools such as checklists to follow a standardized teaching and assessment script. The American Heart Association (AHA) Advanced Cardiovascular Life Support (ACLS) training program relies on simulation for teaching the trainees. Conflicting results are observed in the literature regarding the real benefit of using high fidelity simulation in ACLS courses or in ACLS scenarios. In view of the various forms of teaching using simulation, it becomes necessary to identify the most effective method for training the ACLS. Objectives: (1) To develop a checklist that represents the scenario elaborated by the researchers for the care of cardiorespiratory arrest (PCR) using a Likert scale, (2) To compare the effectiveness of high and low fidelity simulation methods in the training of ACLS using the checklist created. Materials and methods: A checklist was developed using items from a previous one and adding more items created by experts. Final adjustments were made based on the training video, before the approval of the final version. Once the checklist was ready to use, an experimental study was conducted with 55 medical students from the Medical Sciences Faculty of Minas Gerais (FCM-MG) of the 3rd and 4th years. All students completed all phases of the study. Thirty seven were female (67.3%) and the average age was 21.7 ± 1.46 years. The training followed the following steps: (1) Theoretical and practical training of students randomly distributed in groups: experimental (n = 30), which carried out training in high-fidelity simulation and control group (n = 25), of low fidelity. (2) Subsequently, the teams were subjected to a practical assessment of the team's performance using the checklist. Results: Thirty (81.1%) out of 37 checklist items assessed by the experts were scored the highest grade by all of them in a scale from 1 to 4, other six items (16.2%d) were scored 3 by at least one evaluator, and only one (2.7%) was scored 1. Highest grade was scored for 91.9% of the items, exceeding the 85% goal. All students completed the study. Thirty-seven were female and the average age was 21.7 ± 1.46 years. The high fidelity group was compose mainly by females (90.9%) and received more training in emergency and acute care (60.6%, p = 0.002). Practical performance scores were similar for both groups (p = 0.14). Conclusion: The designed checklist based on the 2015 guidelines of the AHA proved to be reliable, with high agreement between the experts. By assessing different types of simulation, this study suggested that there was no advantage in the use of high-fidelity teaching methods.Item Delineamento epidemiológico do câncer do colo do útero no Brasil e da cobertura de estratégias de prevenção, com auxílio de modelo geoespacial, para fundamentar ações para seu controle(Faculdade Ciências Médicas de Minas Gerais, 2020-07-31) Pescuite, Luana Tamara; Rodrigues, Angélica NogueiraIntroduction: According to the latest data from the World Health Organization (WHO), cervical cancer (CC) was classified as the fourth female tumor in incidence and mortality in the world. In Brazil, the National Cancer Institute (INCA) predict around 16,710 new cases for the 2020-2022 triennium, with an estimated risk of 16.35 cases per 100 thousand women, and registered 6,526 deaths in 2018, corresponding to the third tumor in incidence (except non-melanoma tumors) and the fourth in mortality. The Ministry of Health (MS), in partnership with INCA, developed the Brazilian Guidelines for Cervical Cancer Screening, which determine the cervical cytology collection in patients aged 25 to 64 years. The MnS has incorporated a tetravalent vaccine against subtypes 6, 11, 16 and 18 of HPV for girls aged 9 to 14 years old and boys aged 11 to 14 years old. Objectives: CC's epidemiological profile at national level and by federative units, relating incidence and mortality together with the coverage of screening and immunization programs, determining priority areas for intervention through improvements in public health policies. Material and Methods: Ecological study evaluating data on incidence, mortality, vaccination coverage against HPV in girls aged 9 to 14 years and proportion of Pap screening in women aged 25 to 64 years, provided by the MS and INCA. Using the geospatial model, the variables were classified by states and maps were elaborated from the overlap of these variables for visualization and comparison of deficient areas, conceiving a geographical representation of the priority areas for directing interventions by health managers. Results: Seven of the 27 (25.9%) Brazilian states have an incidence of more than 20 cases per 100,000. There is a greater burden of the disease in the North, where all states, except Roraima, have an incidence of more than 18.85 cases per 100,000 women per year, and where all states, without exception, have a mortality rate greater than 6.93 cases per 100,000 women per year. Our analysis also shows an overlap of higher incidence and higher mortality from CC concentrated in the northern region of the country (states of Acre, Amapá, Amazonas, Pará, Roraima, Tocantins) and in a state in the northeast region (Maranhão). Brazil's geographic mapping highlighted a national disparity in HPV vaccination and Pap coverage, both with low median rates. Conclusion: Despite the promise of the recent implantation of HPV vaccination, its full impact will take decades to occur, and these data argue that continuous efforts are needed to improve access to screening and treatment for CC and reduce the lives lost by this preventable disease. The results also suggest that vaccination rates against HPV are below the target, at the risk of repeating Pap test trajectory: an efficient but underutilized tool for CC control.Item Função sexual e alterações metabólicas e hormonais em mulheres usuárias de anticoncepcionais hormonais e não hormonais de longa permanência(Faculdade Ciências Médicas de Minas Gerais, 2020-07-15) Moreira, Igor Fernando de Aquino; Almeida, Alessandra Maciel; Rezende, Bruno AlmeidaBackground: Female sexual dysfunction is a common condition that negatively impacts the emotional health and quality of life of the affected individuals. Long-acting reversible contraceptives (LARCs) are becoming increasingly popular due to their effectiveness and convenience. LARCs can be hormonal (etonogestrel releasing implant—ENG and Levonorgestrel intrauterine system—LNG) or non-hormonal (copper intrauterine device— CuIUD and copper silver intrauterine device—SIUD). There are very few studies that assess the influence on LARCS on sexual function are lacking.This study aimed to assess changes in sexual function as well as metabolic and hormonal parameters in women after implantation with LARCs. Methods: In this prospective cohort study, we assessed 80 women who visited the Military Police Hospital in Brazil for LARCs placement. The study participants were divided into 4 groups according to the type of LARC received: ENG n=17; LNG n=21, CuIUD n=18 and SIUD n=23. The four groups were evaluated twice (prior to LARC placement and approximately 3 months later) for sexual function, using the Female Sexual Function Index (FSFI) and Female Sexual Quotient (QS-F) questionnaires. Metabolic and hormonal parameters were also assessed using blood tests. p<0.05 was considered to indicate statistical significance. Results: We observed an improvement in sexual function with CuIUD placement according to QS-F (p<0.017) and SIUD (FSFI: p=0.06 and QS-F: p<0.001). However, ENG worsened sexual function according to FSFI and QS-F (p<0.001 and p=0.003), across all domains. A decrease in sex hormone-binding globulin (SHBG) was observed for all groups (LNG: p=0.019; ENG: p=0.024; CuIUD: p=0.010; SIUD: p=0.022) and an increase in total testosterone levels (p=0.007 and p = 0.003) and prolactin (p=0.049 and p=0.001) with CuIUD and SIUD placement. Hemoglobin levels increased with LIS (p<0.001) and ENG (p=0.025) and decreased with CuIUD placement (p<0.001). Conclusion: The use of non-hormonal LARCS improved sexual function, especially in the desire domain. Etonogestrel implants, had a negative influence on sexual function, probably by blocking ovarian function, and thus reducing the production of androgens and estrogens. SIUD placement was superior as it improved sexual function, interfered less with hormonal levels, and did not decrease hemoglobin levels.Item Análise eletromiográfica e propriedades clinimétricas do teste muscular manual da cinesiologia aplicada(Faculdade Ciências Médicas de Minas Gerais, 2020-03-13) Oliveira, Décio Gomes de; Kirkwood, Renata NoceBackground: The Applied Kinesiology’s manual muscle test (AK-MMT) is a clinical assessment tool that can be used to identify motor control changes in neurologically healthy subjects. The AK-MMT classifies muscles as ‘facilitated’ or ‘inhibited’ and the hypothesis that explains this difference is that inhibited muscles present a latency delay. Objective: Investigate the hypothesis of the latency delay in inhibited muscles and test the clinimetric properties of the AK-MMT. Methods: A cross-sectional and methodological study was conducted in 38 participants with a mean age of 41.1 years (SD 14.8). Electromyography integrated with an electrical goniometer and a hand-held dynamometer were used to measure latency, angular displacement and muscle force of the gluteus medius muscles, respectively. Inter- and intra rater reliability of two examiners with different levels of experience were obtained using Intraclass Correlation Coefficient (ICC). Muscle force, latency and joint angular displacement were compared between groups (facilitated vs. inhibited) using Mann-Whitney U test. Latency and angular displacement were also compared within groups by paring the participants that presented facilitated gluteus medius in one side and inhibited in the opposite one using the Wilcoxon paired test. For the concurrent validity of the AK-MMT in classifying an inhibited muscle as weak was conducted the receiver operating characteristic curve (ROC curve), by using as the test variable the strength test obtained with the dynamometer. Results: Intra- and inter-examiner reliability was excellent, with ICC’s > 0.9. When the whole sample was considered there was no significant difference in latency, but the Wilcoxon paired test showed a significantly difference delay in latency time of the inhibited muscles (mean 0.10 s vs. 0.18 s, p=0.007) compared to the facilitated gluteus medius. Force and peak force of the inhibited gluteus medius were significantly decreased compared to the facilitated ones. Joint angular displacement was significantly greater in the inhibited group. ROC curve showed an area under the curve of 0.743, demonstrating that the classification of the most experienced examiner discriminated the force between groups (p=0.001), which means that the test has concurrent validity. Conclusion: The results have demonstrated that AK-MMT has good clinimetric properties and support the hypothesis that the AK-MMT is sensitive to differences in strength and latency. This means that physical therapists have now a tool to identify neuromuscular dysfunctions that is reliable, valid and easy to be applied in clinical environment. In addition to providing information about the strength and quality of muscle contraction, the use of TMM AK can facilitate the development of therapeutic strategies aimed at correcting motor control dysfunctions, commonly overlooked in the treatment of acute pain and degenerative musculoskeletal disorders.Item Custos da cirurgia robótica: revelando os verdadeiros vilões(Faculdade Ciências Médicas de Minas Gerais, 2021-04-06) Martins, Yves Melo Rodrigues; Wainstein, Alberto Julius Alves; Santos, Fernando Augusto de VasconcellosINTRODUCTION: High costs of robot-assisted radical prostatectomy (RARP) represent a major drawback of this technology. Considering the financial impact arising from new health care technologies, it is essential to improve the knowledge of factors that influence costs. OBJECTIVE: This study aimed to evaluate the main drivers of RARP hospitalization costs, in addition to assess the relation between clinical, pathological, intraoperative and postoperative variables and the hospitalization costs. MATERIALS AND METHODS: Cross-sectional study of a single private healthcare institution, in which 474 hospitalizations related to RARP between February 2018 and December 2019 were analyzed. Clinical, pathological, intraoperative and postoperative characteristics were considered in the study, including surgical experience. The association between variables and total direct costs was analyzed by simple and multiple linear regression. RESULTS: The main driver of RARP hospitalization costs was the robotic surgical supplies (60.5%), followed by the operation room (OR) time (15.2%). Procedures performed by surgeons with 15 or more cases of surgical experience were associated with a 6.9% decrease in costs in simple linear regression analysis. In multiple linear regression analysis, the following variables were associated with increased costs: American Society of Anesthesiologists (ASA) score 3 (p< 0.001), a one-hour increase in OR time (p < 0.001), increased utilization of polymeric clips packs (p < 0.001), longer length of hospital stay (p< 0.001) and. There was a 11.5% reduction in costs with the use of four robotic instruments instead of five (p < 0.001). CONCLUSIONS: Among clinical and pathological characteristics, only the severity of comorbidities was associated with hospitalization costs. Surgical experience may have an important role in reducing costs. The costs of hospitalization were mainly influenced by the OR time, use of surgical supplies and length of hospital stay. Reducing the number of robotic instruments used in RARP represented the potentially modifiable factor with the greatest impact on cost reduction.Item Perfil dos pacientes submetidos a revisão de artroplastia de quadril com reconstrução utilizando enxerto de banco de osso realizadas em um serviço de referência(Faculdade Ciências Médicas de Minas Gerais, 2020-12-21) Gontijo, Thiago de Carvalho; Leopoldino, Amanda Aparecida Oliveira; Polese, Janaine CunhaBackground: The revision of total hip arthroplasty (RATQ) using a bone graft from a musculoskeletal tissue bank is a large, highly complex surgical procedure, with high costs, in a relatively restricted number of patients. Aims: To determine the epidemiological profile of patients undergoing RATQ, with bone graft from a tissue bank at a reference service. Material and methods: Observational cross-sectional study with the analyses of the medical records of patients undergoing the procedure from 2013 to 2019. As collections were made in medical records by two trained teachers, they were evaluated in an inter-examiner reliability analysis to ensure the reproducibility and safety of the collections. The initial data were collected from the sample by random selection of medical records and analyzed from the calculation of the Kappa index, for dichotomous variables, and by the Intraclass Correlation Coefficient for quantitative variables, which showed satisfactory reliability indexes. 36 variables were collected, such as quantitative data such as age, time between primary total arthroplasty (THA) and the review with use of bone allograft, previous surgeries, number of comorbidities and medications, length of stay in intensive care and hospital stay, blood transfusion, time from the first assessment to surgery and number of postoperative complications. In addition to variables such as sex, place of residence, presentation of the graft, previous complications, comorbidities, presence of contralateral THA, smoking, alcoholism, among others. In the treatment of the final data, descriptive statistics were used, in addition to the percentage to treat the variables in terms of frequency. Pearson's correlation coefficient was used to verify the correlations between the selected quantitative variables and the t test for comparison between groups. Results: 67 hips were analyzed, 53% men, with a mean age of 63.2 years, with 52.2% coming from the metropolitan region. More than half (53.7%) were hypertensive and only 10.4% were diabetic, with an average number of comorbidities of 1.16. Thirty-two patients (47.8%) had no history of RATQ. Loosening of the implants was the most common cause of surgery 89.6%. The average THA time and the revision evaluated were 178.4 months. They used ground graft in 66.7%. When comparing, those with the use of structured graft, in relation to the impacted ground graft, had a higher number of previous surgeries (p = 0.01) and a longer time elapsed between THA (p = 0.03). Conclusion: A sample of younger elderly patients was found, with few comorbidities, possibly with access to treatment facilitated by living in the metropolitan region. The time between the first prosthesis, and the number of procedures on the hip, showed a statistically positive difference in the group using structured grafts, generally used in larger bone defects, compared to the group using the crushed and impacted bone graft.Item Preditores de mortalidade hospitalar nos pacientes submetidos a angioplastia primária(Faculdade Ciências Médicas de Minas Gerais, 2021-04-23) Castro, Pedro Paulo Neves de; Moura, Isabel Cristina Gomes; Pena, José Luiz BarrosIntroduction: Cardiovascular diseases (CVD) are the main cause of morbidity and mortality in Brazil. Ischemic heart disease is the cause of the highest number of deaths among CVDs. The primary angioplasty (PCI) consists of a mechanical treatment to reopen a blocked coronary artery related to acute myocardial infarction with ST-segment elevation. It´s the preferred treatment strategy since it can be performed promptly. Stratifying the risk of death of patients in this context is essential for decision-making and clinical research. Objectives: identify factors related to the outcome of death in patients undergoing PCI. Material and methods: Case-control study, using a national registry as a data source. This registry as a result of the voluntary collaboration of the members of the Brazilian society of hemodynamics and interventional cardiology called the National Cardiovascular Interventions Center (CENIC). The patients were divided into two groups, in the first (cases) the data on patients who died and in the second group (control), patients who underwent the procedure and who survived were allocated. The variables were selected based on previous studies. The association between each variable and the death outcome was assessed using a simple logistic regression model, variables with p <0.20 were included in multiple models using the stepwise strategy. The fit quality was assessed using the Hosmer-Lemeshow test. The results were presented as odds ratios (OR) with the respective 95% confidence intervals (95% CI). It was considered significant p <0.05. Results: 26,990 records were analyzed, of which 18,834 (69.8%) were male, with a mean age of 61.5 ± 12 years. The total number of deaths was 904 and the overall mortality rate was 3.3%. In the multivariate analysis, the main variables related to the death outcome were age> 60 years (60 to 69 years with OR 2,004 [1,336; 3,076], 70 to 79 years OR 2,462 [1,635; 3,789], and ≥ 80 years OR 3,688 [2,384; 5,812], Killip II, III and IV (II with OR 2,718 [1,919; 3,827], III OR 8,139 [5,672; 11,637] and IV OR 19,833 [14,851; 26,688]), severe ventricular dysfunction (OR 3,625 [2,393; 5,675]) and infarction after the intervention (OR 5.006 [2,568; 9,460]) were associated with a lower risk of death, male gender (OR 0.789 [0.635; 0.981]), dyslipidemia (OR 0.689 [0.558; 0.850]), TIMI 2 and 3 (2 with OR 0.593 [0.409; 0.857] and 3 OR) 0.176 [0.133; 0.235]) and the number of lesions treated (OR 0.859 [0.785; xi 0.938]). Conclusion: The predictors of mortality in patients undergoing PCI were: Killip classification, reinfarction, advanced age, severe global left ventricular dysfunction, female, and post-intervention TIMI 0 / I flow. The identification of these data can be useful in stratification and care for patients with coronary disease